The American Cleaning Institute (ACI)

Ask ACI: The Science of Removing Dirt and Bacteria

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What’s the science behind how cleaning products remove dirt and bacteria?

Cleaning products work by leveraging chemistry and biology to break down, lift, and eliminate unwanted substances from surfaces. Most cleaning agents contain active ingredients—such as surfactants, enzymes, or disinfectants—that target specific types of dirt and microorganisms.

Surfactants are molecules that reduce surface tension, allowing water to spread and penetrate grime. They surround and loosen particles of grease, oil, or dirt so they can be rinsed away easily. Enzymatic cleaners, for example, also use biological enzymes to break apart organic stains like food, urine, or pet messes, making them highly effective for tough jobs.

When it comes to bacteria and germs, disinfectants and sanitizers are formulated to destroy or deactivate microbes. They work by breaking down cell walls or interfering with the metabolic processes of bacteria and viruses. Some products combine cleaning and disinfecting action, ensuring surfaces are both visually clean and hygienically safe.

For more information, see the science of cleaning or get more resources at ExplorationClean.org.

Updated: April 7, 2026